Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648356 | 0.82 | ALDH1A1 (1.00) | HSD17B10KDM4EALDH1A1HPGDGRM1 | |
| SCHEMBL12648678 | 0.82 | ALDH1A1 (1.00) | HSD17B10KDM4EALDH1A1HPGDGRM1 | |
| SCHEMBL12648353 | 0.82 | ALDH1A1 (1.00) | HSD17B10KDM4EALDH1A1HPGDGRM1 | |
| SCHEMBL3164267 | 0.80 | CA12 (0.62) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9269593 | 0.78 | CA12 (0.51) | HSD17B10KDM4EALDH1A1HPGDGRM1 | |
| SCHEMBL19273251 | 0.78 | CA12 (0.59) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21366578 | 0.76 | CA12 (0.57) | KDM4EALDH1A1KMT2AGAACA12 | |
| SCHEMBL10723439 | 0.76 | TDP1 (0.70) | HSD17B10KDM4EALDH1A1HPGDGRM1 | |
| SCHEMBL449665 | 0.76 | TDP1 (0.70) | HSD17B10KDM4EALDH1A1HPGDGRM1 | |
| SCHEMBL3478437 | 0.76 | TDP1 (0.70) | HSD17B10KDM4EALDH1A1HPGDGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CHLSN, PTMS, SRMS | HSD17B10 2950/4885KDM4E 3796/4885ALDH1A1 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.