Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044962 | 0.79 | F2 (0.35) | F2ELANECTSGCTRCSMN1; SMN2 | |
| SCHEMBL23475164 | 0.75 | SMN1; SMN2 (0.34) | F2ELANECTSGCTRCSMN1; SMN2 | |
| SCHEMBL10256918 | 0.73 | LMNA (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14529344 | 0.71 | NSD2 (0.37) | SMN1; SMN2 | |
| SCHEMBL11049022 | 0.71 | — | — | |
| SCHEMBL754287 | 0.70 | CA12 (0.32) | PIK3CD | |
| SCHEMBL11620444 | 0.70 | CA12 (0.32) | PIK3CD | |
| SCHEMBL6584171 | 0.70 | ACHE (0.50) | CHRM2CHRM4CHRM5CHRM1SMN1; SMN2 | |
| SCHEMBL14529349 | 0.70 | SMN1; SMN2 (0.39) | CHRM1SMN1; SMN2 | |
| SCHEMBL835259 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279996-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | BARBIER LINDSAY BURNS | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279996-A1 | NOVEL ANALGESIC THAT BINDS FILAMIN A | FLNA, OPRL1, FLNB | CHRM2 698/4885CHRM4 1292/4885CHRM5 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.