Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119340 | 0.93 | CCR2 (0.40) | CCR2KCNH2CCR1 | |
| SCHEMBL13074450 | 0.87 | CCR2 (0.37) | CCR2KCNH2CCR1 | |
| SCHEMBL13011454 | 0.83 | CCR2 (0.38) | CCR2KCNH2CCR1 | |
| SCHEMBL1119775 | 0.81 | CCR2 (0.41) | CCR2KCNH2CCR1 | |
| SCHEMBL1119354 | 0.80 | CCR2 (0.41) | CCR2KCNH2CCR1 | |
| SCHEMBL13074570 | 0.80 | KCNH2 (0.41) | CCR2KCNH2CCR1 | |
| SCHEMBL13074812 | 0.79 | CCR2 (0.37) | CCR2KCNH2 | |
| SCHEMBL1119683 | 0.77 | SIGMAR1 (0.42) | CCR2KCNH2CCR1 | |
| SCHEMBL1119323 | 0.77 | CCR2 (0.44) | CCR2KCNH2CCR1 | |
| SCHEMBL13074452 | 0.77 | CCR2 (0.34) | CCR2KCNH2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129843-A1 | DIHYDRONAPHTHYRIDINYL AND RELATED COMPOUNDS FOR USE IN TREATING OPHTHALMOLOGICAL DISORDERS | CYTOPATHFINDER, INC. (JP) | 2010-11-11 | — | — | WO | disclosed |
| WO-2009076512-A1 | CARBOXAMIDΞ COMPOUNDS AND THEIR USE AS CHEMOKINE RECEPTOR AGONISTS | EPIX DELAWARE, INC. (US) | 2009-06-18 | — | — | WO | disclosed |