Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.79 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.79 |
| ▸ | ECE1 | P42892 | 2/20 | 0.79 |
| ▸ | MUS81 | Q96NY9 | 2/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | RRM1 | P23921 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18876543 | 0.90 | DNM1 (0.79) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| SCHEMBL25474226 | 0.90 | DNM1 (0.79) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| Dynasore SCHEMBL30917221 | 0.88 | DNM1 (1.00) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| Dynasore SCHEMBL29385895 | 0.88 | DNM1 (1.00) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| Dynasore SCHEMBL29695524 | 0.88 | DNM1 (1.00) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| Dynasore SCHEMBL16342920 | 0.88 | DNM1 (1.00) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| Dynasore SCHEMBL4570231 | 0.88 | DNM1 (1.00) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| Dynasore SCHEMBL847982 | 0.88 | DNM1 (1.00) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| Dynasore SCHEMBL30961945 | 0.88 | DNM1 (1.00) | DNM1ECE2ECE1MUS81L3MBTL1 | |
| SCHEMBL18876545 | 0.87 | L3MBTL1 (0.75) | DNM1ECE2ECE1MUS81L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432465-B1 | USE OF DYNAMIN RING STABILIZERS | CHILDREN S MEDICAL RES INST (AU) | 2015-07-22 | — | — | EP | disclosed |
| WO-2010132959-A1 | USE OF DYNAMIN RING STABILIZERS | CHILDREN'S MEDICAL RESEARCH INSTITUTE (AU) | 2010-11-25 | — | — | WO | disclosed |