Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.74 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.74 |
| ▸ | ECE1 | P42892 | 2/20 | 0.74 |
| ▸ | MUS81 | Q96NY9 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | SI | P14410 | 1/20 | 0.65 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17327760 | 0.89 | L3MBTL1 (0.79) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL6635439 | 0.89 | L3MBTL1 (0.82) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL5149469 | 0.89 | L3MBTL1 (0.82) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL8925781 | 0.89 | L3MBTL1 (0.82) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL25474226 | 0.87 | DNM1 (0.79) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL18876543 | 0.87 | DNM1 (0.79) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL12868832 | 0.87 | DNM1 (0.71) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL13074793 | 0.87 | DNM1 (0.79) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL17327816 | 0.87 | L3MBTL1 (0.75) | L3MBTL1DNM1ECE2ECE1MUS81 | |
| SCHEMBL14983909 | 0.86 | DNM1 (0.82) | L3MBTL1DNM1ECE2ECE1MUS81 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144965-A1 | MARMELIN ANALOGS AND METHODS OF USE IN CANCER TREATMENT | THE UNIVERSITY OF KANSAS | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144965-A1 | MARMELIN ANALOGS AND METHODS OF USE IN CANCER TREATMENT | COIL, MUC1, MAN2B2 | L3MBTL1 3214/4885DNM1 3453/4885ECE2 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.