Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 12/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12456871 | 0.82 | SLC5A1 (0.50) | SLC5A2SLC5A1NPC1RAB9ASLC28A3 | |
| SCHEMBL13921313 | 0.81 | TYR (0.57) | SLC5A2SLC5A1NPC1RAB9ATYR | |
| SCHEMBL9507333 | 0.78 | PYGB (0.53) | SLC28A3 | |
| SCHEMBL7215928 | 0.78 | PYGB (0.53) | SLC28A3 | |
| SCHEMBL17080338 | 0.78 | L3MBTL1 (0.46) | SLC28A3TYR | |
| SCHEMBL27775938 | 0.78 | L3MBTL1 (0.46) | SLC28A3TYR | |
| SCHEMBL16934775 | 0.78 | L3MBTL1 (0.46) | SLC28A3TYR | |
| SCHEMBL28909059 | 0.78 | L3MBTL1 (0.46) | SLC28A3TYR | |
| SCHEMBL5032748 | 0.78 | TYR (0.71) | SLC5A2SLC5A1ACHETYR | |
| SCHEMBL14120404 | 0.78 | TYR (0.71) | SLC5A2SLC5A1ACHETYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127363-A1 | TOPOSIOMERASE INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-11-04 | — | — | WO | disclosed |