SCHEMBL17080338

SCHEMBL17080338

O=C(CO)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ LGALS8 O00214 2/20 0.45
▸ GAA P10253 1/20 0.45
▸ TYR P14679 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ PTPN1 P18031 1/20 0.44
▸ PYGB P11216 1/20 0.44
▸ SLC28A3 Q9HAS3 2/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28909059 1.00 L3MBTL1 (0.46) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL27775938 1.00 L3MBTL1 (0.46) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL16934775 1.00 L3MBTL1 (0.46) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL6410535 0.89 LGALS8 (0.56) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL1097983 0.89 LGALS8 (0.56) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL229813 0.89 LGALS8 (0.56) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL17938837 0.89 L3MBTL1 (0.46) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL12613799 0.86 LGALS8 (0.50) L3MBTL1LGALS8GAATYRMAPT
SCHEMBL9507333 0.86 PYGB (0.53) L3MBTL1LGALS8GAAMAPTPYGB
SCHEMBL1098459 0.86 LGALS8 (0.50) L3MBTL1LGALS8GAATYRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590117-B2 Hexose derivatives, preparation and uses thereof FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) 2026-03-31 — — US disclosed
US-20230357301-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) 2023-11-09 — — US disclosed
US-11708387-B2 Hexose derivatives, preparation and uses thereof FACULDADE DE CIÊNCIAS DA UNIVERSIDADE DE LISBOA (PT) 2023-07-25 — — US disclosed
CN-115448964-A Hexose derivatives and their formulations and use 里斯本大学科学与技术学院 2022-12-09 — — CN disclosed
US-20180170955-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF UNIVERSIDADE NOVA DE LISBOA (PT) 2018-06-21 — — US disclosed
EP-3116886-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF Faculdade De Ciências da Universidade de Lisboa (PT) 2017-01-18 — — EP disclosed
WO-2015137838-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF EXTREMOCHEM, LDA. (PT) 2015-09-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180170955-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF HK1, SLC5A1, HK2 L3MBTL1 3975/4885LGALS8 1014/4885GAA 1568/4885
US-20230357301-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF HK1, SLC5A1, HK2 L3MBTL1 3975/4885LGALS8 1014/4885GAA 1568/4885
US-12590117-B2 Hexose derivatives, preparation and uses thereof SLC5A1, HK1, SLC5A2 L3MBTL1 4199/4885LGALS8 345/4885GAA 2176/4885
US-11708387-B2 Hexose derivatives, preparation and uses thereof HK1, SLC5A1, HK2 L3MBTL1 3975/4885LGALS8 1014/4885GAA 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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