Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.48 |
| ▸ | F3 | P13726 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17798927 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL18920303 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL17798929 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL162447 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL162446 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL23327089 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL162448 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL25271398 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL20839272 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL272699 | 0.92 | ALDH1A1 (0.41) | ALDH1A1CYP19A1PPARGOXER1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383380-B1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | BIOZEP AS (NO) | 2023-01-04 | — | — | EP | disclosed |
| US-20190284129-A1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | BIOZEP AS (NO) | 2019-09-19 | — | — | US | disclosed |
| US-20180346408-A1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | BIOZEP AS (NO) | 2018-12-06 | — | — | US | disclosed |
| EP-3383380-A1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | Biozep AS (NO) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017093732-A1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | BIOZEP AS (NO) | 2017-06-08 | — | — | WO | disclosed |
| EP-2248798-A1 | Novel lipid compounds | Pronova BioPharma Norge AS (NO) | 2010-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284129-A1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | APOB, ALOX12, NR1H2 | ALDH1A1 417/4885CYP19A1 884/4885PPARG 392/4885 |
| US-20180346408-A1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | NR1H2, NR1H3, APOB | ALDH1A1 618/4885CYP19A1 1093/4885PPARG 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.