Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PDE2A | O00408 | 6/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077046 | 0.85 | ACACB (0.54) | ACACBPDE2AALOX5 | |
| SCHEMBL3722378 | 0.85 | ACACB (0.51) | ACACBMGLLHCRTR1TDP1 | |
| SCHEMBL13076454 | 0.84 | ACACB (0.59) | ACACBALOX5HCRTR1TDP1 | |
| SCHEMBL30186632 | 0.83 | ACACB (0.63) | ACACBPDE2A | |
| SCHEMBL30202951 | 0.83 | ACACB (0.63) | ACACBPDE2A | |
| SCHEMBL3719867 | 0.80 | ACACA (0.60) | ACACB | |
| SCHEMBL3721454 | 0.77 | ACACB (0.47) | ACACBPDE2AALOX5 | |
| SCHEMBL21295116 | 0.76 | ACACB (0.56) | ACACB | |
| SCHEMBL3721936 | 0.75 | CYP17A1 (0.47) | ACACBHCRTR1TDP1 | |
| SCHEMBL3719875 | 0.74 | ALOX5 (0.74) | ACACBPDE2AALOX5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |