Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.54 |
| ▸ | ACACA | Q13085 | 14/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719867 | 0.92 | ACACA (0.60) | ACACBACACA | |
| SCHEMBL13076352 | 0.85 | ACACB (0.49) | ACACBPDE2AALOX5 | |
| SCHEMBL3721454 | 0.85 | ACACB (0.47) | ACACBACACAPDE2AALOX5 | |
| SCHEMBL30202951 | 0.85 | ACACB (0.63) | ACACBACACAPDE2A | |
| SCHEMBL30186632 | 0.85 | ACACB (0.63) | ACACBACACAPDE2A | |
| SCHEMBL3726452 | 0.84 | ACACB (0.59) | ACACBACACAALOX5 | |
| SCHEMBL3720746 | 0.84 | ACACB (0.52) | ACACBACACA | |
| SCHEMBL3717475 | 0.83 | ACACB (0.73) | ACACBACACAALOX5 | |
| SCHEMBL3808755 | 0.83 | ACACB (0.73) | ACACBACACAALOX5 | |
| SCHEMBL3717628 | 0.82 | ACACB (0.47) | ACACBACACAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |