Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BCR | P11274 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059546 | 0.91 | GAA (0.41) | PORCNMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL13580369 | 0.81 | CYP17A1 (0.40) | MAPTKMT2ACYP3A4 | |
| SCHEMBL13075262 | 0.78 | CNR1 (0.38) | MEN1LMNAKMT2AKCNK3KCNK9 | |
| SCHEMBL10059504 | 0.77 | PDPK1 (0.53) | ALDH1A1HDAC2ABL1BCRHDAC3 | |
| SCHEMBL13075035 | 0.76 | HSD17B10 (0.53) | NPC1ALDH1A1LMNARAB9A | |
| SCHEMBL13284149 | 0.75 | ACSS2 (0.38) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL13284321 | 0.75 | BRD4 (0.45) | HDAC1 | |
| SCHEMBL13284320 | 0.75 | GAA (0.37) | MEN1ALDH1A1MAPTKMT2AKCNK3 | |
| SCHEMBL10059845 | 0.73 | RXFP1 (0.45) | NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL10079118 | 0.72 | NOX4 (0.42) | MEN1ALDH1A1LMNARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135470-A1 | PIFENIDONE DERIVATIVES FOR TREATING BRONCHIAL ASTHMA | INTERMUNE, INC. (US) | 2010-11-25 | — | — | WO | disclosed |