Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284320 | 0.90 | GAA (0.37) | KMT2AMEN1GAASMN1; SMN2RIPK1 | |
| SCHEMBL10059495 | 0.89 | SMN1; SMN2 (0.46) | CNR1GAAAHRSMN1; SMN2NOX4 | |
| SCHEMBL13580369 | 0.87 | CYP17A1 (0.40) | CNR1KMT2ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL13075035 | 0.81 | HSD17B10 (0.53) | GAALMNANOX4 | |
| SCHEMBL13284149 | 0.81 | ACSS2 (0.38) | KMT2AMEN1LMNA | |
| SCHEMBL10059853 | 0.80 | NOX4 (0.44) | KMT2AMEN1GAAAHRSMN1; SMN2 | |
| SCHEMBL10059415 | 0.79 | RAB9A (0.49) | KMT2AMEN1GAASMN1; SMN2MGLL | |
| SCHEMBL10059512 | 0.79 | GAA (0.49) | GAAAHRSMN1; SMN2NOX4HTR1A | |
| SCHEMBL13076864 | 0.78 | PORCN (0.38) | KMT2AMEN1LMNAKCNK3KCNK9 | |
| SCHEMBL13284321 | 0.78 | BRD4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135470-A1 | PIFENIDONE DERIVATIVES FOR TREATING BRONCHIAL ASTHMA | INTERMUNE, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010132864-A1 | METHODS OF TREATING HIV PATIENTS WITH ANTI-FIBROTICS | INTERMUNE, INC. (US) | 2010-11-18 | — | — | WO | disclosed |