SCHEMBL1307703

SCHEMBL1307703

c1ccc(Cc2cnnnn2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
CALM1 P0DP23 1/20 0.44
MAOB P27338 1/20 0.39
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HRH3 Q9Y5N1 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
CD74 P04233 1/20 0.37
MIF P14174 1/20 0.37
AOC3 Q16853 1/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
KCNMA1 Q12791 1/20 0.35
HRH4 Q9H3N8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30850470 1.00 ALDH1A1 (0.46) ALDH1A1CALM1MAOBRAB9ASMN1; SMN2
SCHEMBL132209 0.75 ALDH1A1 (0.50) ALDH1A1CALM1MAOBRAB9ASMN1; SMN2
SCHEMBL27072915 0.70 CALM1 (0.55) ALDH1A1CALM1MAOBRAB9ASMN1; SMN2
SCHEMBL2129775 0.68 ALDH1A1 (0.52) ALDH1A1CALM1MAOBRAB9ASMN1; SMN2
SCHEMBL21986304 0.67 HPGD (0.50) ALDH1A1SMN1; SMN2L3MBTL1HPGD
SCHEMBL3819703 0.67 BCL2 (0.42) ALDH1A1CALM1HPGD
SCHEMBL8040113 0.66 ALDH1A1 (0.44) ALDH1A1CALM1MAOBRAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL16246102 0.66 HPGD (0.49) ALDH1A1SMN1; SMN2L3MBTL1HPGD
SCHEMBL11330543 0.66 KCNH2 (0.62) ALDH1A1CALM1MAOBRAB9ASMN1; SMN2
SCHEMBL31167981 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071270-A1 ON-SEQUENCER IMAGING FLOWCELL REUSE ILLUMINA, INC. (US) 2026-03-12 US claimed
US-6740655-B2 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 4-SPECIFIC INHIBITORS REDUCE EOSINOPHIL INFLUX TO THE LUNGS; SIDE EFFECT REDUCTION; ANTIINFLAMMATORY AGENT; ANTIALLERGENS; RESPIRATORY SYSTEM DISORDERS, ESPECIALLY ASTHMA PFIZER INC 2004-05-25 US claimed
US-20030144300-A1 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes PFIZER PRODUCTS INC. 2003-07-31 US claimed
EP-1252157-A1 PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES Pfizer Products Inc. (US) 2002-10-30 EP claimed
EP-1140784-A2 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2001-10-10 EP claimed
WO-2001057025-A1 PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES PFIZER PRODUCTS INC. (US) 2001-08-09 WO claimed
WO-2000037422-A2 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2000-06-29 WO claimed
US-20260071270-A1 ON-SEQUENCER IMAGING FLOWCELL REUSE ILLUMINA, INC. (US) 2026-03-12 US disclosed
EP-4678764-A2 NANOPARTICLE WITH SINGLE SITE FOR TEMPLATE POLYNUCLEOTIDE ATTACHMENT ILLUMINA, INC. (US) 2026-01-14 EP disclosed
EP-4081657-B1 NANOPARTICLE WITH SINGLE SITE FOR TEMPLATE POLYNUCLEOTIDE ATTACHMENT ILLUMINA INC (US) 2025-10-29 EP disclosed
US-20250236865-A1 METHODS FOR CAPTURING LIBRARY DNA FOR SEQUENCING ILLUMINA, INC. 2025-07-24 US disclosed
EP-4587588-A1 NANOPARTICLE WITH POLYNUCLEOTIDE BINDING SITE AND METHOD OF MAKING THEREOF ILLUMINA, INC. (US) 2025-07-23 EP disclosed
EP-4186529-B1 IMPROVED ANTIBODY-PAYLOAD CONJUGATES (APCS) PREPARED BY SITE-SPECIFIC CONJUGATION UTILIZING GENETIC CODE EXPANSION VERAXA BIOTECH GMBH (DE) 2025-07-09 EP disclosed
EP-1252157-A1 PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES Pfizer Products Inc. (US) 2002-10-30 EP disclosed
WO-2001057025-A1 PYRIMIDINE CARBOXAMIDES USEFUL AS INHIBITORS OF PDE4 ISOZYMES PFIZER PRODUCTS INC. (US) 2001-08-09 WO disclosed
EP-0219852-B1 CHARTREUSIN DERIVATIVES, SALTS THEREOF, ANTITUMOROUS COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR PRODUCING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 1992-02-05 EP disclosed
US-5064945-A Antitumor Agents ISHIHARA SANGYO KAISHA, LTD. (JP) 1991-11-12 US disclosed
US-4927919-A ANTITUMOR AGENTS ISHIHARA SANGYO KAISHA, LTD. (JP) 1990-05-22 US disclosed
EP-0231244-A1 6-ALKYLIDENE PENEMS BEECHAM GROUP PLC (GB) 1987-08-12 EP disclosed
WO-1987000525-A1 6-ALKYLIDENE PENEMS BEECHAM GROUP P.L.C. (GB) 1987-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071270-A1 ON-SEQUENCER IMAGING FLOWCELL REUSE NT5C3B, SMCHD1, NT5C2 ALDH1A1 3823/4885CALM1 2117/4885MAOB 1891/4885
US-20030144300-A1 Pyrimidine carboxamides useful as inhibitors of pde4 isozymes PDE12, PDE4A, PDE4B ALDH1A1 978/4885CALM1 2276/4885MAOB 410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.