Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | ACACB | O00763 | 9/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CDC42 | P60953 | 1/20 | 0.47 |
| ▸ | RAC1 | P63000 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720090 | 0.88 | ACACB (0.46) | ALOX5ACACBACACA | |
| SCHEMBL3726745 | 0.88 | ACACB (0.57) | ACACBAKR1C3AKR1C2ACACALMNA | |
| SCHEMBL3719875 | 0.86 | ALOX5 (0.74) | ALOX5ACACBCNR1PTGS2AKR1C3 | |
| SCHEMBL3798078 | 0.86 | ALOX5 (0.57) | ALOX5ACACBCNR1PTGS2AKR1C3 | |
| SCHEMBL3724111 | 0.83 | ACACB (0.77) | ALOX5ACACBPTGS2AKR1C3AKR1C2 | |
| SCHEMBL3722350 | 0.80 | TAS1R3 (0.56) | ALOX5ACACBACACA | |
| SCHEMBL3726184 | 0.78 | ACACB (0.66) | ALOX5ACACBACACA | |
| SCHEMBL13077043 | 0.78 | ACACB (0.57) | ALOX5ACACBACACA | |
| SCHEMBL3720744 | 0.78 | ACACB (0.51) | ALOX5ACACBACACA | |
| SCHEMBL3722414 | 0.77 | ACACB (0.56) | ACACBAKR1C3AKR1C2ACACALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |