Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077584 | 1.00 | GHSR (0.46) | GHSRCRHR1NOS3NOS1NOS2 | |
| SCHEMBL3728002 | 0.92 | GHSR (0.52) | GHSRCRHR1TRPV4 | |
| SCHEMBL3729644 | 0.92 | GHSR (0.52) | GHSRCRHR1TRPV4 | |
| SCHEMBL3728004 | 0.92 | GHSR (0.52) | GHSRCRHR1TRPV4 | |
| SCHEMBL3722803 | 0.91 | GHSR (0.48) | GHSRCRHR1TRPV4MCHR1 | |
| SCHEMBL3729623 | 0.91 | GHSR (0.48) | GHSRCRHR1TRPV4MCHR1 | |
| SCHEMBL3722802 | 0.91 | GHSR (0.48) | GHSRCRHR1TRPV4MCHR1 | |
| SCHEMBL3731703 | 0.90 | GHSR (0.49) | GHSRCRHR1TRPV4 | |
| SCHEMBL3731706 | 0.90 | GHSR (0.49) | GHSRCRHR1TRPV4 | |
| SCHEMBL13039915 | 0.88 | GHSR (0.48) | GHSRCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825155-B2 | Oxindole derivative as feeding control agent | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | GPR119, OXTR, CCKAR | GHSR 9/4885CRHR1 139/4885NOS3 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.