Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607395 | 0.85 | NPC1 (0.39) | NPC1RAB9ARXFP1ALDH1A1MAP4K4 | |
| SCHEMBL16487523 | 0.75 | ADORA3 (0.36) | NPC1RAB9AALDH1A1DGAT1KDM4E | |
| SCHEMBL1160646 | 0.74 | NPC1 (0.42) | NPC1RAB9ARXFP1ALDH1A1MAP4K4 | |
| SCHEMBL10238098 | 0.71 | NPC1 (0.39) | NPC1RAB9ARXFP1ALDH1A1MAP4K4 | |
| SCHEMBL13058552 | 0.70 | NPC1 (0.39) | NPC1RAB9ARXFP1ALDH1A1MAP4K4 | |
| SCHEMBL11963696 | 0.67 | NPC1 (0.32) | NPC1RAB9ARXFP1 | |
| SCHEMBL13078144 | 0.65 | PTGS1 (0.31) | — | |
| SCHEMBL2763495 | 0.64 | NPC1 (0.45) | NPC1RAB9ARXFP1ALDH1A1MAP4K4 | |
| SCHEMBL9287104 | 0.64 | PDE1A (0.34) | NPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL13078091 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279868-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279868-A1 | NOVEL HERBICIDES | DDT, HPD, HSD17B1 | NPC1 4588/4885RAB9A 4207/4885RXFP1 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.