Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060697 | 0.90 | POLB (0.50) | SMN1; SMN2NPC1HTTGAAEPHX1 | |
| SCHEMBL1060694 | 0.90 | POLB (0.50) | SMN1; SMN2NPC1HTTGAAEPHX1 | |
| SCHEMBL16054838 | 0.82 | LMNA (0.44) | SMN1; SMN2NPC1HTTGAAEPHX1 | |
| SCHEMBL16054834 | 0.82 | LMNA (0.44) | SMN1; SMN2NPC1HTTGAAEPHX1 | |
| SCHEMBL16054837 | 0.82 | LMNA (0.44) | SMN1; SMN2NPC1HTTGAAEPHX1 | |
| SCHEMBL10065266 | 0.82 | CYP2D6 (0.53) | SMN1; SMN2NPC1HTTGAACYP2D6 | |
| SCHEMBL16054840 | 0.82 | LMNA (0.44) | SMN1; SMN2NPC1HTTGAAEPHX1 | |
| SCHEMBL19974764 | 0.81 | EPHX1 (0.52) | NPC1EPHX1CYP2D6ALDH1A1CA12 | |
| SCHEMBL23543513 | 0.81 | KMT2A (0.54) | NPC1EPHX1CYP2D6ALDH1A1CA12 | |
| SCHEMBL19974830 | 0.79 | KMT2A (0.49) | NPC1EPHX1CYP2D6ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838893-B1 | LINKER, ANTIBODY-DRUG CONJUGATE INCLUDING SAME, AND USE THEREOF | ACAD OF MILITARY MEDICAL SCIENCES (CN) | 2023-04-19 | — | — | EP | disclosed |
| EP-3838893-A1 | LINKER, ANTIBODY-DRUG CONJUGATE INCLUDING SAME, AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2021-06-23 | — | — | EP | disclosed |
| US-7829967-B2 | Resin for optical-semiconductor-element encapsulation containing polyimide and optical semiconductor device obtained with the same | NITTO DENKO CORPORATION (JP) | 2010-11-09 | — | — | US | disclosed |