Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060694 | 0.91 | POLB (0.50) | CYP2D6TDP1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL1060697 | 0.91 | POLB (0.50) | CYP2D6TDP1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL16054838 | 0.83 | LMNA (0.44) | CYP2D6TDP1LMNAPLGPLAT | |
| SCHEMBL16054837 | 0.83 | LMNA (0.44) | CYP2D6TDP1LMNAPLGPLAT | |
| SCHEMBL16054834 | 0.83 | LMNA (0.44) | CYP2D6TDP1LMNAPLGPLAT | |
| SCHEMBL16054840 | 0.83 | LMNA (0.44) | CYP2D6TDP1LMNAPLGPLAT | |
| SCHEMBL13078096 | 0.82 | SMN1; SMN2 (0.55) | CYP2D6POLBSMN1; SMN2HTTNPC1 | |
| SCHEMBL2985534 | 0.77 | CYP2D6 (0.81) | CYP2D6TDP1LMNAPLGPLAT | |
| SCHEMBL3903603 | 0.77 | CYP2D6 (0.81) | CYP2D6TDP1LMNAPLGPLAT | |
| SCHEMBL1080643 | 0.76 | POLB (0.38) | CYP2D6TDP1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052161-A1 | DENTAL COMPOSITION | DENTSPLY DE TREY GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |