Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289444 | 0.89 | EDNRB (0.39) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL2284490 | 0.84 | KMT2A (0.38) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL2286465 | 0.81 | GAA (0.39) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL14445636 | 0.78 | NPC1 (0.32) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL5497132 | 0.78 | EDNRB (0.37) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL14446467 | 0.78 | NPC1 (0.32) | CXCR2NPC1CYP1A2RAB9AEDNRB | |
| SCHEMBL3741461 | 0.77 | NPC1 (0.35) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL2288861 | 0.75 | NPC1 (0.35) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL2288811 | 0.75 | NPC1 (0.35) | NPC1CYP1A2RAB9AEDNRBEDNRA | |
| SCHEMBL12416005 | 0.74 | HSP90AA1 (0.35) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829703-B2 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2010-11-09 | — | — | US | disclosed |
| US-7482308-B2 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2009-01-27 | — | — | US | disclosed |
| US-20080312084-A1 | DIFLUOROMETHANESFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-12-18 | — | — | US | disclosed |
| US-20070197390-A1 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| EP-1750510-B1 | DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197390-A1 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | PFAS, DDT, HDHD5 | CXCR2 1825/4885NPC1 4678/4885CYP1A2 676/4885 |
| US-20080312084-A1 | DIFLUOROMETHANESFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | HDHD5, PFAS, DDT | CXCR2 1452/4885NPC1 4580/4885CYP1A2 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.