Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286974 | 0.88 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1CTSANPSR1OPRM1 | |
| SCHEMBL5499243 | 0.78 | CTSA (0.36) | HSP90AA1HSP90AB1CTSAKCNJ5KCNJ3 | |
| SCHEMBL2292233 | 0.76 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1CTSANPSR1KCNJ5 | |
| SCHEMBL2287144 | 0.76 | CYP1A2 (0.37) | HSP90AA1HSP90AB1PDCD1LG2CD274 | |
| SCHEMBL2286121 | 0.75 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1CTSANPSR1OPRM1 | |
| SCHEMBL13078652 | 0.74 | CXCR2 (0.33) | CTSA | |
| SCHEMBL5503157 | 0.74 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1CTSANPSR1OPRM1 | |
| SCHEMBL11993262 | 0.74 | PDE2A (0.36) | HSP90AA1HSP90AB1KCNJ5KCNJ3CCR4 | |
| SCHEMBL2286995 | 0.74 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1CTSANPSR1OPRM1 | |
| SCHEMBL28761320 | 0.73 | NUDT1 (0.36) | HSP90AA1HSP90AB1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008484-B2 | Use of sulfonanilides as agricultural and horticultural fungicide | BAYER CROPSCIENCE AG (DE) | 2011-08-30 | — | — | US | disclosed |
| US-20070219199-A1 | Use of Sulfonanilides as Agricultural and Horticultural Fungicide | BAYER CROPSCIENCE AG (DE) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219199-A1 | Use of Sulfonanilides as Agricultural and Horticultural Fungicide | CBR3, CYP51A1, CBR1 | HSP90AA1 3876/4885HSP90AB1 3783/4885THRB 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.