Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567407 | 0.92 | EPHX2 (0.37) | TSHREPHX2THRBASGR1 | |
| SCHEMBL28568019 | 0.86 | THRB (0.39) | EPHX2THRBALDH1A1 | |
| SCHEMBL825473 | 0.83 | TSHR (0.38) | TSHREPHX2ALDH1A1 | |
| SCHEMBL4401855 | 0.82 | TSHR (0.41) | TSHREPHX2ALDH1A1 | |
| SCHEMBL44041 | 0.81 | ALDH1A1 (0.35) | TSHRTHRBALDH1A1 | |
| SCHEMBL4403811 | 0.81 | TSHR (0.43) | TSHREPHX2THRB | |
| SCHEMBL4399200 | 0.81 | TSHR (0.43) | TSHREPHX2THRB | |
| SCHEMBL4401860 | 0.81 | TSHR (0.43) | TSHREPHX2THRB | |
| SCHEMBL14580049 | 0.81 | THRB (0.41) | TSHREPHX2THRBALDH1A1 | |
| SCHEMBL14580047 | 0.80 | ALDH1A1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833690-B2 | Photoacid generators and lithographic resists comprising the same | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2010-11-16 | — | — | US | disclosed |
| US-7776505-B2 | High resolution resists for next generation lithographies | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2010-08-17 | — | — | US | disclosed |