Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119421 | 0.87 | ALDH1A1 (0.41) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL25779307 | 0.78 | LMNA (0.40) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL14778772 | 0.74 | ALDH1A1 (0.43) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL26926934 | 0.72 | KDM4E (0.34) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL13369382 | 0.70 | ALDH1A1 (0.46) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL16372871 | 0.69 | USP2 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL16373067 | 0.69 | USP2 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL13936320 | 0.69 | KDM4E (0.41) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL27129729 | 0.69 | CA1 (0.39) | TSHR | |
| SCHEMBL27129870 | 0.69 | CA1 (0.39) | ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8282959-B2 | Branched end reactants and polymeric hydrogel tissue adhesives therefrom | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-10-09 | — | — | US | disclosed |
| US-20100086678-A1 | BRANCHED END REACTANTS AND POLYMERIC HYDROGEL TISSUE ADHESIVES THEREFROM | E.I.DUPONT DE NEMOURS AND COMPANY (DE) | 2010-04-08 | — | — | US | disclosed |