SCHEMBL25779307

SCHEMBL25779307

CCOC(C)COCCOS(C)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MMP9 P14780 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12119421 0.87 ALDH1A1 (0.41) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL25779341 0.84 KDM4E (0.39) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL22167732 0.82 LMNA (0.37) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL24089553 0.81 KDM4E (0.40) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL14778772 0.81 ALDH1A1 (0.43) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL26465758 0.80 KDM4E (0.44) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL13079446 0.78 KDM4E (0.34) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL25779313 0.78 TDP1 (0.48) LMNAALDH1A1TSHRTDP1
SCHEMBL25779352 0.76 KDM4E (0.44) LMNAKDM4EUSP2ALDH1A1MMP9
SCHEMBL25779334 0.76 KDM4E (0.48) LMNAKDM4EUSP2ALDH1A1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212103-A1 POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF HANMI PHARM. CO., LTD. (KR) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212103-A1 POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF RPN2, MPDU1, RPN1 LMNA 2253/4885KDM4E 3528/4885USP2 1181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.