Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.59 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.59 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.59 |
| ▸ | RRM1 | P23921 | 1/20 | 0.48 |
| ▸ | NMT2 | O60551 | 2/20 | 0.47 |
| ▸ | NMT1 | P30419 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 4/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | CD40 | P25942 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13079511 | 0.84 | GNAI3 (0.54) | GNAI3GNAO1GNAI1RRM1NMT2 | |
| SCHEMBL22930819 | 0.81 | GNAI3 (0.59) | GNAI3GNAO1GNAI1RRM1NMT2 | |
| SCHEMBL13079191 | 0.80 | DPP8 (0.51) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL29399779 | 0.80 | DPP8 (0.51) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL13311473 | 0.80 | NMT1 (0.64) | GNAI3GNAO1GNAI1RRM1NMT2 | |
| SCHEMBL13636959 | 0.79 | GNAI3 (0.54) | GNAI3GNAO1GNAI1RRM1NMT2 | |
| SCHEMBL18031023 | 0.79 | BIRC2 (0.42) | NMT2NMT1 | |
| SCHEMBL7565869 | 0.79 | NOD1 (0.65) | GNAI3GNAO1GNAI1RRM1NMT2 | |
| SCHEMBL18059234 | 0.79 | GNAI3 (0.69) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL31633172 | 0.79 | GNAI3 (0.84) | GNAI3GNAO1GNAI1RRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338643-B2 | Reagent for introduction of protein or gene | WASEDA UNIVERSITY (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | WASEDA UNIVERSITY (JP) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | C1S, SGMS1, CERT1 | GNAI3 3465/4885GNAO1 2905/4885GNAI1 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.