Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962849 | 0.86 | KMT2A (0.53) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049706 | 0.85 | PTPN1 (0.45) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049701 | 0.84 | LMNA (0.57) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049721 | 0.81 | MAPK14 (0.49) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049711 | 0.80 | KDM4E (0.49) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049764 | 0.80 | PTPN1 (0.43) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049759 | 0.80 | CYP19A1 (0.52) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049703 | 0.78 | PTGS2 (0.59) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049776 | 0.78 | LMNA (0.39) | CYP3A4KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL13049719 | 0.78 | CYP19A1 (0.55) | CYP3A4KMT2AALDH1A1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7837981-B2 | Methods for imaging soluble A-beta | GENERAL ELECTRIC COMPANY (US) | 2010-11-23 | — | — | US | disclosed |