SCHEMBL13049719

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13049766	0.85	MAPT (0.49)	CYP19A1CYP11B1CYP11B2TNKSPARP1
	SCHEMBL13049700	0.81	FBP1 (0.44)	CYP19A1CYP11B1CYP11B2KMT2AMEN1
	SCHEMBL2962849	0.80	KMT2A (0.53)	CYP19A1CYP11B1CYP11B2KMT2AMEN1
	SCHEMBL13049706	0.79	PTPN1 (0.45)	KMT2AMEN1L3MBTL1KDM4EALDH1A1
	SCHEMBL13049701	0.78	LMNA (0.57)	TNKSPARP1TNKS2PARP2KMT2A
	SCHEMBL13080176	0.78	CYP3A4 (0.42)	CYP19A1CYP11B1CYP11B2KMT2AMEN1
	SCHEMBL13049703	0.78	PTGS2 (0.59)	KMT2AMEN1ALDH1A1LMNAUSP2
	SCHEMBL13049761	0.78	ALDH1A1 (0.52)	KMT2AMEN1MAPTL3MBTL1ALDH1A1
	SCHEMBL13049764	0.77	PTPN1 (0.43)	CYP19A1CYP11B1CYP11B2KMT2AMEN1
	SCHEMBL13049712	0.77	PTGS2 (0.45)	KMT2AMEN1MAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.