Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TAOK3 | Q9H2K8 | 3/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18602758 | 0.88 | FAAH (0.39) | FAAHALOX5PPARGPPARALMNA | |
| SCHEMBL9289071 | 0.88 | LMNA (0.38) | FAAHALOX5PPARGPPARALMNA | |
| SCHEMBL16299335 | 0.86 | FAAH (0.36) | FAAHALOX5PPARGPPARALMNA | |
| SCHEMBL16299327 | 0.85 | FAAH (0.37) | FAAHALOX5PPARGPPARALMNA | |
| SCHEMBL9290215 | 0.83 | ALDH1A1 (0.34) | FAAHLMNACYP1A2KMT2ACYP2C9 | |
| SCHEMBL10262710 | 0.82 | FAAH (0.37) | FAAHALOX5PPARGPPARALMNA | |
| SCHEMBL9289915 | 0.80 | LMNA (0.39) | FAAHALOX5PPARGPPARALMNA | |
| SCHEMBL13082978 | 0.80 | FAAH (0.38) | FAAHALOX5PPARGPPARALMNA | |
| SCHEMBL9289892 | 0.80 | MEN1 (0.32) | FAAHLMNAKMT2A | |
| SCHEMBL6128441 | 0.79 | FAAH (0.38) | FAAHALOX5PPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129057-A2 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |