SCHEMBL13083063

SCHEMBL13083063

Cc1c(CN)cc(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.33
DPP4 P27487 2/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23303816 0.81 MEN1 (0.33) LOXL2
SCHEMBL8090926 0.79 ALDH1A1 (0.34)
SCHEMBL3972407 0.78 LOXL2 (0.37) LOXL2DPP4
SCHEMBL24935139 0.78 CYP19A1 (0.37)
SCHEMBL28235044 0.77 DPP4 (0.31) DPP4
SCHEMBL8082934 0.76 HMGCR (0.34)
SCHEMBL13068796 0.74 LOXL2 (0.34) LOXL2
SCHEMBL8097116 0.74 DPP4 (0.37) DPP4
SCHEMBL3676581 0.73 MPO (0.35) LOXL2
SCHEMBL18588928 0.73 LOXL2 (0.33) LOXL2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010134636-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROL OF PLANT DISEASES 住友化学株式会社 (JP) 2010-11-25 WO disclosed