SCHEMBL13085019

SCHEMBL13085019

Cc1cc(Cl)cc(C(N)=O)c1NC(=O)c1cc(Cn2nnc(C(F)(C(F)(F)F)C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.34
SLC2A1 P11166 3/20 0.33
SLC2A3 P11169 3/20 0.33
SLC2A4 P14672 3/20 0.33
SLC2A2 P11168 1/20 0.33
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
MALT1 Q9UDY8 1/20 0.30
ADRA1D P25100 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686615 0.94 SLC2A1 (0.33) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL685546 0.94 SLC2A1 (0.35) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL31060080 0.94 SLC2A1 (0.35) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085438 0.94 DHODH (0.32) DHODHALDH1A1SMN1; SMN2ADRA1D
SCHEMBL13085398 0.93 DHODH (0.35) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL11928476 0.93 SLC2A1 (0.32) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085478 0.93 DHODH (0.34) DHODHALDH1A1SMN1; SMN2MALT1
SCHEMBL13085339 0.92 SLC2A1 (0.38) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085439 0.92 DHODH (0.33) DHODHALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL13085301 0.92 DHODH (0.33) DHODHALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 DHODH 2604/4885SLC2A1 2324/4885SLC2A3 2023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.