SCHEMBL686615

SCHEMBL686615

Cc1cc(Cl)cc(C(N)=O)c1NC(=O)c1cc(Cn2nnc(C(F)(F)C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 3/20 0.33
SLC2A3 P11169 3/20 0.33
SLC2A4 P14672 3/20 0.33
DHODH Q02127 3/20 0.33
SLC2A2 P11168 1/20 0.33
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
MALT1 Q9UDY8 1/20 0.30
ADRA1D P25100 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11928476 0.96 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL13085019 0.94 DHODH (0.34) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL685546 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL31060080 0.94 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL15489002 0.94 DHODH (0.33) DHODHALDH1A1SMN1; SMN2MALT1
SCHEMBL13085015 0.94 ADRA1D (0.31) DHODHALDH1A1SMN1; SMN2ADRA1D
SCHEMBL13085348 0.93 SLC2A1 (0.31) SLC2A1SLC2A3SLC2A4SLC2A2ALDH1A1
SCHEMBL10075289 0.93 DHODH (0.33) DHODHALDH1A1SMN1; SMN2MALT1
SCHEMBL686522 0.92 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4DHODHSLC2A2
SCHEMBL10075290 0.92 DHODH (0.32) DHODHALDH1A1SMN1; SMN2HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2012-01-26 US disclosed
WO-2012010525-A2 USE OF ANTHRANILIC ACID AMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY WATERING, MIXING WITH SOIL, DRENCH TREATMENT, DROPLET APPLICATION, INJECTION INTO THE SOIL, STEMS OR BLOSSOMS, IN HYDROPONIC SYSTEMS, BY TREATING THE PLANTING HOLE OR IMMERSION APPLICATION, FLOATING OR SEED BOX APPLICATION OR BY THE TREATMENT OF SEEDS, AND FOR INCREASING THE STRESS TOLERANCE IN PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2012-01-26 WO disclosed
WO-2012004221-A2 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES BAYER CROPSCIENCE AG (DE) 2012-01-12 WO disclosed
US-20120010073-A1 Anthranilamides in combination with fungicides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed
WO-2011157778-A1 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDE AND ACARICIDE PROPERTIES BAYER CROPSCIENCE AG (DE) 2011-12-22 WO disclosed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides AADAC, NAAA, ANTXR2 SLC2A1 4803/4885SLC2A3 4685/4885SLC2A4 4817/4885
US-20120010073-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 SLC2A1 4485/4885SLC2A3 4386/4885SLC2A4 4434/4885
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS CDY1; CDY1B, DHX9, DHX29 SLC2A1 2970/4885SLC2A3 2492/4885SLC2A4 2995/4885
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties ACHE, ACAT1, ACAT2 SLC2A1 4309/4885SLC2A3 4229/4885SLC2A4 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.