SCHEMBL13085129

SCHEMBL13085129

CNC(=O)c1cc(C)cc(C)c1NC(=O)c1cc(Cn2nnnc2C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.33
NTRK1 P04629 2/20 0.32
SLC2A1 P11166 2/20 0.32
SLC2A3 P11169 2/20 0.32
SLC2A4 P14672 2/20 0.32
SLC2A2 P11168 1/20 0.32
MALT1 Q9UDY8 1/20 0.31
PDE10A Q9Y233 1/20 0.31
NR3C1 P04150 2/20 0.31
LMNA P02545 2/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
STIM1 Q13586 1/20 0.30
ORAI1 Q96D31 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL684736 0.94 NTRK1 (0.33) DHODHNTRK1SLC2A1SLC2A3SLC2A4
SCHEMBL11928398 0.94 NTRK1 (0.34) DHODHNTRK1SLC2A1SLC2A3SLC2A4
SCHEMBL11928601 0.93 DHODH (0.34) DHODHNTRK1SLC2A1SLC2A3SLC2A4
SCHEMBL13085016 0.93 DHODH (0.35) DHODHNTRK1SLC2A1SLC2A3SLC2A4
SCHEMBL13085025 0.92 DHODH (0.33) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL29454973 0.92 SLC2A1 (0.37) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL798557 0.92 SLC2A1 (0.37) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL685899 0.91 DHODH (0.31) DHODHNTRK1SLC2A1SLC2A3SLC2A4
SCHEMBL11928503 0.91 CRHR1 (0.38) L3MBTL1
SCHEMBL13085032 0.90 NTRK1 (0.34) DHODHNTRK1MALT1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2379526-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER IP GMBH (DE) 2015-05-27 EP disclosed
EP-2484676-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER CROPSCIENCE AG (DE) 2015-01-21 EP disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
WO-2010069502-A2 TETRAZOLE SUBSTITUTED ANTHRANILIC ACID AMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 DHODH 2604/4885NTRK1 2506/4885SLC2A1 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.