SCHEMBL13085147

SCHEMBL13085147

CC(C)NC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(Cn2nnc(C(F)(F)C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 1/20 0.32
SLC16A1 P53985 1/20 0.32
MCTS1 Q9ULC4 1/20 0.32
DHODH Q02127 3/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CAPN1 P07384 1/20 0.31
WDR5 P61964 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075294 0.94 DHODH (0.32) SLC16A3SLC16A1MCTS1DHODHALDH1A1
SCHEMBL13085401 0.94 DHODH (0.33) SLC16A3SLC16A1MCTS1DHODHALDH1A1
SCHEMBL13085066 0.94 DHODH (0.34) SLC16A3SLC16A1MCTS1DHODHALDH1A1
SCHEMBL13085148 0.93 DGAT2 (0.32)
SCHEMBL13085323 0.92 ALDH1A1 (0.33) DHODHALDH1A1SMN1; SMN2
SCHEMBL13085123 0.92 IDO1 (0.33) ALDH1A1SMN1; SMN2WDR5
SCHEMBL13085124 0.91 ALDH1A1 (0.33) DHODHALDH1A1SMN1; SMN2
SCHEMBL13085204 0.91 ALDH1A1 (0.32) DHODHALDH1A1SMN1; SMN2
SCHEMBL15488988 0.91 ALDH1A1 (0.32) DHODHALDH1A1SMN1; SMN2
SCHEMBL11928141 0.91 DHODH (0.31) SLC16A3SLC16A1MCTS1DHODHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC16A3 1919/4885SLC16A1 2291/4885MCTS1 1643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.