SCHEMBL13085437

SCHEMBL13085437

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(C(C)n2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.32
MALT1 Q9UDY8 4/20 0.31
TRPV1 Q8NER1 1/20 0.31
NTRK1 P04629 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623670 0.94 DHODH (0.32) DHODHMALT1TRPV1NTRK1
SCHEMBL13085527 0.92 SLC2A1 (0.33) DHODHMALT1
SCHEMBL13085367 0.87 DHODH (0.31) DHODHMALT1TRPV1
SCHEMBL13085493 0.85 SLC2A1 (0.33) DHODHMALT1
SCHEMBL13085579 0.85 SLC2A1 (0.33) DHODHMALT1
SCHEMBL13085447 0.84 SLC2A1 (0.37) DHODH
SCHEMBL13085366 0.84 SLC2A1 (0.34) MALT1TRPV1
SCHEMBL685542 0.84 DHODH (0.33) DHODHMALT1TRPV1NTRK1
SCHEMBL782368 0.83 CARM1 (0.39) MALT1TRPV1
SCHEMBL13085596 0.82 DHODH (0.31) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 DHODH 2604/4885MALT1 4312/4885TRPV1 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.