SCHEMBL13085447

SCHEMBL13085447

Cc1cc(C#N)cc(C(N)=O)c1NC(=O)c1cc(C(C)n2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 17/20 0.37
SLC2A3 P11169 17/20 0.37
SLC2A4 P14672 17/20 0.37
SLC2A2 P11168 9/20 0.37
ADORA3 P0DMS8 1/20 0.31
HRH2 P25021 1/20 0.31
HRH1 P35367 1/20 0.31
PTGER4 P35408 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
PRKDC P78527 1/20 0.31
ATM Q13315 1/20 0.31
ATR Q13535 1/20 0.31
DHODH Q02127 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085527 0.93 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085493 0.93 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085579 0.93 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL13085366 0.91 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL15971748 0.85 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2PIK3CA
SCHEMBL31060079 0.85 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2PIK3CA
SCHEMBL10075523 0.85 SLC2A1 (0.40) SLC2A1SLC2A3SLC2A4SLC2A2ADORA3
SCHEMBL13085437 0.84 DHODH (0.32) DHODH
SCHEMBL2623670 0.84 DHODH (0.32) DHODH
SCHEMBL960289 0.84 SLC2A1 (0.42) SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.