SCHEMBL31060079

SCHEMBL31060079

Cc1cc(C#N)cc(C(N)=O)c1NC(=O)c1cc(C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 6/20 0.38
SLC2A3 P11169 6/20 0.38
SLC2A4 P14672 6/20 0.38
SLC2A2 P11168 3/20 0.38
LIMK1 P53667 2/20 0.35
LIMK2 P53671 2/20 0.35
KMT2A Q03164 1/20 0.34
PKM P14618 1/20 0.34
DHODH Q02127 1/20 0.33
GCK P35557 3/20 0.33
KCNH2 Q12809 3/20 0.33
PDE4B Q07343 3/20 0.33
PDE4A P27815 2/20 0.33
PDE4C Q08493 2/20 0.33
PDE4D Q08499 2/20 0.33
MALT1 Q9UDY8 1/20 0.33
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15971748 1.00 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2LIMK1
SCHEMBL15246061 0.92 LIMK1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2LIMK1
SCHEMBL15971802 0.90 ALDH1A1 (0.37) LIMK1LIMK2DHODHPDE4BMALT1
SCHEMBL31060053 0.90 ALDH1A1 (0.37) LIMK1LIMK2DHODHPDE4BMALT1
SCHEMBL961226 0.89 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL31060063 0.89 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL31060051 0.88 LIMK1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2LIMK1
SCHEMBL15971540 0.88 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL25274851 0.88 TRPV1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2LIMK1
SCHEMBL13318550 0.87 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 SLC2A1 395/4885SLC2A3 825/4885SLC2A4 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.