SCHEMBL13085539

SCHEMBL13085539

Cc1cc(C#N)cc(C(=O)NCC2CC2)c1NC(=O)c1cc(Cn2nnnc2C(F)(F)F)nn1-c1ccccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 8/20 0.34
SLC2A3 P11169 8/20 0.34
SLC2A4 P14672 8/20 0.34
TP53 P04637 2/20 0.33
LMNA P02545 1/20 0.33
CETP P11597 1/20 0.33
CNR1 P21554 1/20 0.33
SLC2A2 P11168 3/20 0.32
CRHR1 P34998 1/20 0.32
USP30 Q70CQ3 1/20 0.32
KLKB1 P03952 3/20 0.32
CNR2 P34972 1/20 0.32
MAPT P10636 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085494 0.92 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085612 0.91 CRHR1 (0.36) SLC2A1SLC2A3SLC2A4CNR1SLC2A2
SCHEMBL11927961 0.91 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL10076317 0.90 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085610 0.89 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL10083277 0.89 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL11928401 0.88 P2RX7 (0.38) SLC2A1SLC2A3SLC2A4CETPSLC2A2
SCHEMBL10076315 0.88 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085496 0.88 CETP (0.35) SLC2A1SLC2A3SLC2A4TP53LMNA
SCHEMBL12242848 0.85 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SLC2A1 2324/4885SLC2A3 2023/4885SLC2A4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.