SCHEMBL13085636

SCHEMBL13085636

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ccc(OC(F)(F)F)cc1Cl

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMURF1 Q9HCE7 2/20 0.37
▸ GPR6 P46095 2/20 0.33
▸ SLC2A1 P11166 6/20 0.32
▸ SLC2A3 P11169 6/20 0.32
▸ SLC2A4 P14672 6/20 0.32
▸ SLC2A2 P11168 1/20 0.32
▸ CACNA1H O95180 2/20 0.31
▸ CACNA1G O43497 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CACNA1C Q13936 1/20 0.31
▸ CACNA1I Q9P0X4 1/20 0.31
▸ SCN9A Q15858 1/20 0.31
▸ TEK Q02763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13090538 0.91 CNR1 (0.33) SMURF1SLC2A1SLC2A3SLC2A4
SCHEMBL10083881 0.89 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL10089902 0.88 IDH1 (0.37) SMURF1GPR6SLC2A1SLC2A3SLC2A4
SCHEMBL13085455 0.87 L3MBTL1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL13085463 0.87 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL10089907 0.86 ABCB1 (0.37) SLC2A1SLC2A3SLC2A4
SCHEMBL13085225 0.86 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL10083882 0.85 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085456 0.84 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2CACNA1H
SCHEMBL10089859 0.84 SLC2A1 (0.37) GPR6SLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484676-B1 Tetrazol-substituted anthranilic acid amides as pesticides BAYER CROPSCIENCE AG (DE) 2015-01-21 — — EP disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 SMURF1 4834/4885GPR6 4039/4885SLC2A1 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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