SCHEMBL13090538

SCHEMBL13090538

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ccc(Cl)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SLC2A1 P11166 4/20 0.32
▸ SLC2A3 P11169 4/20 0.32
▸ SLC2A4 P14672 4/20 0.32
▸ CNR2 P34972 3/20 0.32
▸ SMURF1 Q9HCE7 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085455 0.94 L3MBTL1 (0.36) SLC2A1SLC2A3SLC2A4
SCHEMBL10083881 0.92 SLC2A1 (0.35) CNR1SLC2A1SLC2A3SLC2A4MEN1
SCHEMBL13084903 0.91 NPC1 (0.35) CNR1NPC1ALDH1A1TP53RAB9A
SCHEMBL13085636 0.91 SMURF1 (0.37) SLC2A1SLC2A3SLC2A4SMURF1
SCHEMBL13085463 0.90 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4
SCHEMBL13085225 0.89 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4
SCHEMBL10089990 0.88 CNR1 (0.42) CNR1TP53SLC2A1SLC2A3SLC2A4
SCHEMBL13085456 0.87 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4
SCHEMBL10083882 0.87 SLC2A1 (0.33) CNR1SLC2A1SLC2A3SLC2A4MEN1
SCHEMBL798149 0.87 SLC2A1 (0.36) ALDH1A1SLC2A1SLC2A3SLC2A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 — — US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 CNR1 1936/4885NPC1 4044/4885ALDH1A1 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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