Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | TLR3 | O15455 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298411 | 0.80 | TLR3 (0.34) | ALOX15ALOX12MAPTALDH1A1TLR3 | |
| SCHEMBL25084169 | 0.78 | ALOX15 (0.55) | ALOX15ALOX12MAPTALDH1A1PTGS1 | |
| SCHEMBL31009079 | 0.78 | ALOX15 (0.55) | ALOX15ALOX12MAPTALDH1A1PTGS1 | |
| SCHEMBL1428264 | 0.76 | CYP1A2 (0.36) | TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL351795 | 0.71 | CTNNB1 (0.45) | ALOX15ALOX12NPC1RAB9AHTT | |
| SCHEMBL5752488 | 0.71 | CETP (0.38) | ALOX15ALOX12CNR2CYP4F2CYP4A11 | |
| Nitromethane SCHEMBL5522618 | 0.70 | CYP3A4 (0.54) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9392813 | 0.69 | P2RY6 (0.41) | TTRMAPTALDH1A1PTGS2TSHR | |
| SCHEMBL7233580 | 0.67 | CYP4F2 (0.45) | ALOX15MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9142026 | 0.66 | CNR1 (0.46) | ALOX15ALOX12TTRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140187762-A1 | Optical Sorting Method | MEDICAL RESEARCH COUNCIL (GB) | 2014-07-03 | — | — | US | disclosed |
| EP-1905828-B1 | Optical sorting method | MEDICAL RES COUNCIL (GB) | 2012-08-08 | — | — | EP | disclosed |
| EP-1522581-B1 | Optical sortingmethod | MEDICAL RES COUNCIL (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-7897341-B2 | Optical sorting method | MEDICAL RESEARCH COUNCIL (GB) | 2011-03-01 | — | — | US | disclosed |
| US-20090325236-A1 | Optical sorting method | GRIFFITHS ANDREW | 2009-12-31 | — | — | US | disclosed |
| EP-1141272-B1 | OPTICAL SORTING METHOD | MEDICAL RES COUNCIL (GB) | 2009-11-11 | — | — | EP | disclosed |
| US-20090053700-A1 | Optical sorting method | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2009-02-26 | — | — | US | disclosed |
| EP-1905828-A2 | Optical sorting method | Medical Research Council (GB) | 2008-04-02 | — | — | EP | disclosed |
| EP-1522582-B1 | Optical sorting method | MEDICAL RES COUNCIL (GB) | 2007-07-04 | — | — | EP | disclosed |
| US-20050164239-A1 | Compartmentalizing genetic elements into microcapsules, expressing elements to produce gene products within microcapsules, sorting elements using change in optical properties; in vitro evolution of nucleic acid through repeated mutagenesis | MEDICAL RESEARCH COUNCIL (GB) | 2005-07-28 | — | — | US | disclosed |
| EP-1522582-A2 | Optical sorting method | MEDICAL RESEARCH COUNCIL (GB) | 2005-04-13 | — | — | EP | disclosed |
| EP-1522581-A2 | Optical sortingmethod | Medical Research Council (GB) | 2005-04-13 | — | — | EP | disclosed |
| US-20050037392-A1 | Compartmentalizing genetic elements into microcapsules, expressing elements to produce gene products within microcapsules, sorting elements using change in optical properties; in vitro evolution of nucleic acid through repeated mutagenesis | MEDICAL RESEARCH COUNCIL (GB) | 2005-02-17 | — | — | US | disclosed |
| US-6808882-B2 | ISOLATING PREFERENTIAL NUCLEOTIDE SEQUENCES; OBTAIN NUCLEOTIDE SEQUENCE SAMPLES, ENCAPSULATE INTO MICROCAPSULES, MONITOR GENE EXPRESSION ACTIVITIES | MEDICAL RESEARCH COUNCIL (GB) | 2004-10-26 | — | — | US | disclosed |
| US-20020119459-A1 | Optical sorting method | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2002-08-29 | — | — | US | disclosed |
| EP-1141272-A1 | OPTICAL SORTING METHOD | MEDICAL RESEARCH COUNCIL (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040712-A1 | OPTICAL SORTING METHOD | MEDICAL RESEARCH COUNCIL (GB) | 2000-07-13 | — | — | WO | disclosed |