Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130857 | 0.76 | ALOX15 (0.38) | CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL25192586 | 0.75 | TSHR (0.56) | CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL2298411 | 0.71 | TLR3 (0.34) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1098576 | 0.67 | CTNNB1 (0.41) | — | |
| SCHEMBL67998 | 0.66 | P2RY6 (0.33) | — | |
| SCHEMBL9424845 | 0.66 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL9427783 | 0.64 | AKR1B1 (0.42) | CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL12483210 | 0.61 | HTT (0.44) | CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL22058720 | 0.61 | CA1 (0.46) | TSHR | |
| SCHEMBL24179080 | 0.61 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855725-A2 | CYCLODEXTRIN-BASED POLYMERS CONTAINING PHOTOCLEAVABLE LINKERS FOR DRUG DELIVERY | Insert Therapeutics Inc. (US) | 2007-11-21 | — | — | EP | claimed |
| US-20060210527-A1 | Cyclodextrin-based polymers for therapeutics delivery | INSERT THERAPEUTICS, INC. (US) | 2006-09-21 | — | — | US | claimed |
| WO-2006089007-A2 | CYCLODEXTRIN-BASED POLYMERS CONTAINING PHOTOCLEAVABLE LINKERS FOR DRUG DELIVERY | INSERT THERAPEUTICS, INC. (US) | 2006-08-24 | — | — | WO | claimed |
| EP-3497446-A1 | METHOD AND COMPOSITION FOR DETECTION OF PEPTIDE CYCLIZATION USING PROTEIN TAGS | H. Hoffnabb-La Roche Ag (CH) | 2019-06-19 | — | — | EP | disclosed |
| EP-3286362-A1 | METHOD AND COMPOSITION FOR PEPTIDE CYCLIZATION AND PROTEASE TREATMENT | F. Hoffmann-La Roche AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| WO-2018033478-A1 | METHOD AND COMPOSITION FOR DETECTION OF PEPTIDE CYCLIZATION USING PROTEIN TAGS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-02-22 | — | — | WO | disclosed |
| EP-2300067-B1 | DRUG DELIVERY COMPOSITION | THE QUEEN'S UNIV OF BELFAST (GB) | 2017-10-25 | — | — | EP | disclosed |
| CN-106456831-A | Resin composition suitable for printing and printing method using the same | 莱奥本矿业大学 | 2017-02-22 | — | — | CN | disclosed |
| US-20160136286-A1 | DRUG DELIVERY COMPOSITION | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-05-19 | — | — | US | disclosed |
| US-9271928-B2 | Drug delivery composition | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-03-01 | — | — | US | disclosed |
| WO-2012142480-A1 | CHIMERIC RNA OLIGONUCLEOTIDES AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2012-10-18 | — | — | WO | disclosed |
| US-5874589-A | Methods for synthesizing diverse collections of tetramic acids and derivatives thereof | GLAXO WELLCOME, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| US-5846839-A | Methods for hard-tagging an encoded synthetic library | GLAXO GROUP LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |
| US-5739386-A | PHOTOCLEAVABLE LINKING GROUPS IN SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-14 | — | — | US | disclosed |
| WO-1997041093-A1 | METHODS FOR THE SYNTHESIS OF FMOC PROTECTED AMINES | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-11-06 | — | — | WO | disclosed |
| EP-0776330-A2 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1997-06-04 | — | — | EP | disclosed |
| US-5549974-A | IMMOBILIZATION | AFFYMAX TECHNOLOGIES NV (AN) | 1996-08-27 | — | — | US | disclosed |
| WO-1996000148-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF THIAZOLIDINONES, METATHIAZANONES, AND DERIVATIVES THEREOF | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |
| WO-1996000378-A1 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |
| WO-1994010128-A1 | NOVEL PHOTOREACTIVE PROTECTING GROUPS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160136286-A1 | DRUG DELIVERY COMPOSITION | ECPAS, ABCB11, ABCB1 | CYP1A2 297/4885CYP2C9 167/4885CYP2C19 168/4885 |
| US-20060210527-A1 | Cyclodextrin-based polymers for therapeutics delivery | SI, PAICS, DSC1 | CYP1A2 1292/4885CYP2C9 354/4885CYP2C19 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.