SCHEMBL13086116

SCHEMBL13086116

C=CC(=O)OCOC(=O)Oc1ccc(C(=O)Oc2ccc(-c3ccc(OC(=O)c4ccc(OC(=O)OCOC(=O)C=C)cc4)cc3C)c(C)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.37
LMNA P02545 1/20 0.37
THRB P10828 2/20 0.36
PRSS1 P07477 2/20 0.36
ACR P10323 2/20 0.36
MAPT P10636 7/20 0.36
MEN1 O00255 4/20 0.35
RARA P10276 2/20 0.35
RARB P10826 2/20 0.35
NR1H4 Q96RI1 1/20 0.34
GFER P55789 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GBA1 P04062 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085903 0.94 KMT2A (0.35) KMT2ALMNATHRBPRSS1ACR
SCHEMBL8962275 0.90 THRB (0.39) KMT2ALMNATHRBPRSS1ACR
SCHEMBL12404399 0.88 THRB (0.42) KMT2ALMNATHRBPRSS1ACR
SCHEMBL16449853 0.88 THRB (0.42) KMT2ALMNATHRBPRSS1ACR
SCHEMBL11986111 0.86 RARA (0.36) KMT2ATHRBPRSS1ACRMAPT
SCHEMBL16491594 0.86 KMT2A (0.36) KMT2ALMNATHRBPRSS1ACR
SCHEMBL11986090 0.85 THRB (0.34) KMT2ATHRBPRSS1ACRMAPT
SCHEMBL12404294 0.85 MAOA (0.36) KMT2ATHRBMAPTMEN1RARA
SCHEMBL15397325 0.85 KMT2A (0.46) KMT2ALMNATHRBPRSS1ACR
SCHEMBL16449854 0.85 KMT2A (0.39) KMT2ALMNATHRBPRSS1ACR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100264367-A1 Polymerizable liquid crystal compound, liquid crystal composition, and polymer JNC PETROCHEMICAL CORPORATION (JP) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100264367-A1 Polymerizable liquid crystal compound, liquid crystal composition, and polymer H1-2, H1-0, CPNE4 KMT2A 537/4885LMNA 720/4885THRB 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.