SCHEMBL13086225

SCHEMBL13086225

CC(=O)c1cccc(C(=O)Cl)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
ACMSD Q8TDX5 1/20 0.48
ALDH1A1 P00352 4/20 0.47
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 2/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
RAB9A P51151 1/20 0.40
MCL1 Q07820 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455687 0.89 KDM4E (0.59) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL321127 0.89 KDM4E (0.59) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL6641842 0.86 KDM4E (0.56) KDM4ETDP1ALOX15TSHRACMSD
Hydrochloric Acid SCHEMBL27613793 0.86 KDM4E (0.56) KDM4ETDP1ALOX15TSHRACMSD
Hydrochloric Acid SCHEMBL28930333 0.84 ALDH1A1 (0.58) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL6428673 0.80 KDM4E (0.77) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL27643814 0.80 KDM4E (0.77) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL29793731 0.78 ALDH1A1 (0.50) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL21018216 0.78 KDM4E (0.48) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL29502527 0.78 GRM5 (0.59) KDM4ETDP1ALOX15TSHRACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230144729-A1 SPACER, METHOD FOR MANUFACTURING SAME, AND DISPLAY DEVICE TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2023-05-11 US disclosed
US-20100266507-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100266507-A1 LUMINESCENT COMPOUNDS SQLE, COASY, ZKSCAN2 KDM4E 1279/4885TDP1 4554/4885ALOX15 2714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.