SCHEMBL321127

SCHEMBL321127

O=C(Cl)c1cccc(C(=O)Cl)n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
ACMSD Q8TDX5 1/20 0.59
POLB P06746 1/20 0.50
CYP1A2 P05177 1/20 0.45
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
MCL1 Q07820 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27643814 0.91 KDM4E (0.77) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL13086225 0.89 KDM4E (0.48) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL3044752 0.85 KDM4E (0.44) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL1766284 0.85 TSHR (0.45) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL40454 0.84 GRM5 (0.51) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL29502527 0.84 GRM5 (0.59) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL31197987 0.84 GRM4 (0.45) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL46948 0.84 KDM4E (0.43) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL512860 0.84 GRM5 (0.59) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL3956769 0.84 GRM4 (0.45) KDM4ETDP1ALOX15TSHRACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 571 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119971800-A High-stability anti-pollution efficient composite reverse osmosis membrane and preparation method thereof 中国矿业大学(北京) 2025-05-13 CN claimed
CN-119711169-A High-weather-resistance textile material and preparation method thereof 三明建华纺织有限公司 2025-03-28 CN claimed
CN-119707360-A Color mixture for preventive maintenance of asphalt pavement and preparation method thereof 北京中天路业科技有限公司 2025-03-28 CN claimed
CN-118748246-B Silicon-containing carbon-based negative electrode material and preparation process and application thereof 深圳市明盛新能源科技有限公司 2025-01-21 CN claimed
CN-116102413-B Preparation method of 2-methyl-1, 4-naphthoquinone and intermediate thereof 浙江大学 2024-12-31 CN claimed
CN-118580582-A Nitrile rubber/lignin masterbatch and ABS material and preparation method thereof 中国石油化工股份有限公司 2024-09-03 CN claimed
CN-118406008-A Quinoline modification-based bishydrazide functional pincer compound and synthesis and application thereof 西北民族大学 2024-07-30 CN claimed
CN-114130220-B Preparation method of polytriazine alkali-resistant composite nanofiltration membrane 万华化学集团股份有限公司 2024-06-25 CN claimed
CN-117659643-B Polyester material resistant to wet heat aging and preparation method thereof 扬州君禾薄膜科技有限公司 2024-05-24 CN claimed
CN-117843914-B Preparation method of high-performance self-repairing elastomer material for self-repairing inner tube or other elastic materials 内蒙古科技大学 2024-05-14 CN claimed
CN-111072557-A Amide type Gemini surfactant and preparation method thereof 江南大学 2020-04-28 CN claimed
CN-111039925-A Pyridine-based organic room temperature phosphorescent compound and preparation and application thereof 浙江工业大学 2020-04-21 CN claimed
US-20190282967-A1 SEMIPERMEABLE MEMBRANE AND PREPARATION METHOD THEREOF LORD CORPORATION 2019-09-19 US claimed
US-20120255898-A1 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH & DEVELOPMENT, INC. (US) 2012-10-11 US claimed
WO-2010042250-A2 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH AND DEVELOPMENT, INC. (US) 2010-04-15 WO claimed
US-20100006495-A1 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH AND DEVELOPMENT, INC. (US) 2010-01-14 US claimed
WO-2003082824-A1 SYNTHESIS OF 2,6-DICARBONYLPYRIDINES BOULDER SCIENTIFIC COMPANY (US) 2003-10-09 WO claimed
US-20030187271-A1 Synthesis of 2, 6-dicarbonylpyridines BOULDER SCIENTIFIC COMPANY 2003-10-02 US claimed
EP-0227043-A2 Composite semipermeable membrane and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-01 EP claimed
EP-0198202-A2 Novel N-cyclohexyl-polycarboxamide compound and derivatives thereof, processes for preparing them, and use of them in preparation of host-guest complexes MITSUBISHI CORPORATION (JP) 1986-10-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187271-A1 Synthesis of 2, 6-dicarbonylpyridines DDT, DHPS, PAH KDM4E 1372/4885TDP1 3439/4885ALOX15 1866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.