SCHEMBL6428673

SCHEMBL6428673

CC(=O)c1cccc(C(=O)O)n1

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.77
ALOX15 P16050 2/20 0.77
TSHR P16473 2/20 0.77
ACMSD Q8TDX5 1/20 0.77
TDP1 Q9NUW8 1/20 0.77
LMNA P02545 2/20 0.58
GNE Q9Y223 1/20 0.52
ALDH1A1 P00352 1/20 0.48
ECE1 P42892 1/20 0.47
KMT2A Q03164 1/20 0.46
MGAM O43451 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
P4HTM Q9NXG6 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
HIF1A Q16665 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455687 0.91 KDM4E (0.59) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL6641842 0.88 KDM4E (0.56) KDM4EALOX15TSHRACMSDTDP1
Hydrochloric Acid SCHEMBL27613793 0.88 KDM4E (0.56) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL28437790 0.88 KDM4E (0.90) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL34595 0.88 KDM4E (1.00) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL720696 0.88 KDM4E (1.00) KDM4EALOX15TSHRACMSDTDP1
Hydrochloric Acid SCHEMBL28930333 0.86 ALDH1A1 (0.58) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL3974347 0.85 KDM4E (0.94) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL11294102 0.85 KDM4E (0.94) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL6561776 0.85 KDM4E (0.94) KDM4EALOX15TSHRACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121379303-B Fireproof and corrosion-resistant compressed garbage truck metal box coating and preparation method thereof 湖北凯力专用汽车有限公司 2026-03-31 CN disclosed
CN-121379303-A Fireproof and corrosion-resistant compressed garbage truck metal box coating and preparation method thereof 湖北凯力专用汽车有限公司 2026-01-23 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-2725903-B1 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2020-04-15 EP disclosed
EP-3066094-B1 PYRAZOLE FOR THE TREATMENT AUTOIMMUNE DISORDERS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-08 EP disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
CN-105899505-B Pyrazoles for the treatment of autoimmune disorders 武田药品工业株式会社 2018-08-28 CN disclosed
US-20180188428-A1 NEAR-INFRARED CUT FILTER, METHOD FOR PRODUCING NEAR-INFRARED CUT FILTER, AND SOLID-STATE IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2018-07-05 US disclosed
US-20180188428-A1 NEAR-INFRARED CUT FILTER, METHOD FOR PRODUCING NEAR-INFRARED CUT FILTER, AND SOLID-STATE IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2018-07-05 US disclosed
US-20180175090-A1 NEAR INFRARED ABSORBING COMPOSITION, FILM, NEAR INFRARED CUT FILTER, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2018-06-21 US disclosed
US-8754229-B2 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides DOW AGROSCIENCES, LLC. (US) 2014-06-17 US disclosed
US-20140142137-A1 HIV INTEGRASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (US) 2014-05-22 US disclosed
EP-2725903-A1 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES Dow AgroSciences LLC (US) 2014-05-07 EP disclosed
US-20130245255-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-19 US disclosed
US-20130203987-A1 AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME RIGEL PHARMACEUTICALS, INC. (US) 2013-08-08 US disclosed
US-20130158042-A1 NOVEL COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-06-20 US disclosed
US-20130005574-A1 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES CORTEVA AGRISCIENCE LLC 2013-01-03 US disclosed
WO-2013003740-A1 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2013-01-03 WO disclosed
US-20120128640-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2012-05-24 US disclosed
US-20050148623-A1 Prevent reproduct of aids virus ABBVIE INC. 2005-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245255-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS HCLS1, RUNX1, RCC1 KDM4E 2096/4885ALOX15 2415/4885TSHR 2617/4885
US-20130005574-A1 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES DDT, AADAC, AADAT KDM4E 1083/4885ALOX15 2247/4885TSHR 489/4885
US-20050148623-A1 Prevent reproduct of aids virus SERPINB1, PRSS1, SERPINA3 KDM4E 2995/4885ALOX15 2093/4885TSHR 4830/4885
US-20120128640-A1 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS HCLS1, RUNX1, RCC1 KDM4E 2096/4885ALOX15 2415/4885TSHR 2617/4885
US-20140142137-A1 HIV INTEGRASE INHIBITORS IMPDH1, TYMP, IMPA1 KDM4E 2275/4885ALOX15 3989/4885TSHR 4712/4885
US-20130203987-A1 AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME PRKAG1, PRKAG2, PRKAB1 KDM4E 926/4885ALOX15 3709/4885TSHR 1509/4885
US-20130158042-A1 NOVEL COMPOUNDS GRM5, GRIK5, GRM1 KDM4E 1242/4885ALOX15 2751/4885TSHR 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.