Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086523 | 0.99 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL13086364 | 0.90 | HPGD (0.40) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL13086368 | 0.87 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL2777905 | 0.85 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL13086356 | 0.85 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL2781215 | 0.84 | ALDH1A1 (0.40) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL13086405 | 0.82 | EPHX2 (0.41) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL13086444 | 0.82 | PTGS2 (0.36) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL13086369 | 0.82 | EPHX2 (0.40) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL13086253 | 0.80 | MAPT (0.35) | ALDH1A1GAAMAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |