Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086523 | 0.91 | ALDH1A1 (0.41) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL13086256 | 0.90 | ALDH1A1 (0.42) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL13086369 | 0.85 | EPHX2 (0.40) | HPGDALDH1A1TSHRMAPTEPHX2 | |
| SCHEMBL13086335 | 0.85 | ALDH1A1 (0.42) | HPGDALDH1A1TSHRMAPTEPHX2 | |
| SCHEMBL13086405 | 0.84 | EPHX2 (0.41) | HPGDALDH1A1TSHRMAPTEPHX2 | |
| SCHEMBL13086319 | 0.80 | PTGS2 (0.35) | HPGDALDH1A1TSHRMAPTEPHX2 | |
| SCHEMBL13086356 | 0.77 | ALDH1A1 (0.41) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL13086368 | 0.77 | ALDH1A1 (0.41) | HPGDALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL13086375 | 0.76 | PDE4A (0.44) | HPGDALDH1A1TSHRKDM4EPOLB | |
| SCHEMBL2781215 | 0.76 | ALDH1A1 (0.40) | HPGDALDH1A1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |