Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | TGM2 | P21980 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893434 | 0.85 | MAPT (0.53) | MAPTKLK7KLK5TGM2ALDH1A1 | |
| SCHEMBL7759126 | 0.85 | MAPT (0.53) | MAPTKLK7KLK5TGM2ALDH1A1 | |
| SCHEMBL30600455 | 0.85 | MAPT (0.53) | MAPTKLK7KLK5TGM2ALDH1A1 | |
| SCHEMBL29401091 | 0.85 | MAPT (0.53) | MAPTKLK7KLK5TGM2ALDH1A1 | |
| SCHEMBL2334326 | 0.83 | MAPT (0.68) | MAPTKLK7KLK5TGM2FOLH1 | |
| SCHEMBL3210903 | 0.83 | MAPT (0.68) | MAPTKLK7KLK5TGM2FOLH1 | |
| SCHEMBL2334319 | 0.83 | MAPT (0.68) | MAPTKLK7KLK5TGM2FOLH1 | |
| SCHEMBL10077062 | 0.83 | TGM2 (0.69) | MAPTKLK7KLK5TGM2FOLH1 | |
| SCHEMBL28334172 | 0.83 | ALDH1A1 (0.49) | MAPTKLK7KLK5TGM2ALDH1A1 | |
| SCHEMBL20945354 | 0.82 | TGM2 (0.52) | MAPTKLK7KLK5TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114615-A2 | A FACILE SYSTEM FOR ENCODING UNNATURAL AMINO ACIDS IN MAMMALIAN CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-10-07 | — | — | WO | disclosed |