Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.77 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16833443 | 0.78 | MEN1 (0.65) | KMT2AMEN1CACNA1BAPBA1HTT | |
| SCHEMBL30172583 | 0.76 | KDM4E (0.64) | KMT2AMEN1HTTALDH1A1KDM4E | |
| SCHEMBL662652 | 0.76 | KDM4E (0.64) | KMT2AMEN1HTTALDH1A1KDM4E | |
| SCHEMBL3170222 | 0.75 | CYP1A2 (0.49) | KMT2AMEN1CACNA1BAPBA1HTT | |
| SCHEMBL28267403 | 0.75 | KDM4E (0.62) | KMT2AMEN1HTTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11329279 | 0.75 | KDM4E (0.62) | KMT2AMEN1HTTALDH1A1KDM4E | |
| SCHEMBL12308137 | 0.74 | CACNA1B (0.77) | KMT2AMEN1CACNA1BAPBA1HTT | |
| SCHEMBL7328160 | 0.73 | AKR1C3 (0.48) | KMT2AMEN1HTTALDH1A1KDM4E | |
| SCHEMBL27632452 | 0.73 | AKR1C3 (0.48) | KMT2AMEN1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL10202038 | 0.73 | NPC1 (0.49) | KMT2AMEN1HTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838696-B1 | NOVEL CYANOGUANIDINE COMPOUNDS | LEO PHARMA AS (DK) | 2016-03-09 | — | — | EP | disclosed |
| US-8053446-B2 | Cyanoguanidine compounds | LEO PHARMA A/S (DK) | 2011-11-08 | — | — | US | disclosed |
| US-20080312275-A1 | Novel Cyanoguanidine Compounds | LEO PHARMA A/S (DK) | 2008-12-18 | — | — | US | disclosed |
| EP-1838696-A1 | NOVEL CYANOGUANIDINE COMPOUNDS | Leo Pharma A/S (DK) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006066584-A1 | NOVEL CYANOGUANIDINE COMPOUNDS | LEO PHARMA A/S (DK) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312275-A1 | Novel Cyanoguanidine Compounds | MKI67, CCNA1, COL1A1 | KMT2A 2197/4885MEN1 1685/4885CACNA1B 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.