Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308020 | 0.88 | ABCB1 (0.64) | LMNASMN1; SMN2ABCB1ABCC1MAPT | |
| SCHEMBL1307837 | 0.82 | TUBB4A (0.61) | LMNASMN1; SMN2ABCB1ABCC1MAPT | |
| SCHEMBL1306325 | 0.81 | TUBB4A (0.50) | ABCB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1308648 | 0.81 | ABCB1 (0.60) | LMNASMN1; SMN2ABCB1ABCC1TUBB4A | |
| SCHEMBL1308565 | 0.80 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2ABCB1ABCC1MAPT | |
| SCHEMBL12116691 | 0.80 | LMNA (0.60) | LMNASMN1; SMN2ABCB1MAPTTUBB4A | |
| SCHEMBL1309598 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2ABCB1ABCC1MAPT | |
| SCHEMBL1307176 | 0.80 | ABCB1 (0.55) | LMNASMN1; SMN2ABCB1MAPTTUBB4A | |
| SCHEMBL1308711 | 0.79 | TUBB4A (0.50) | LMNASMN1; SMN2ABCB1ABCC1MAPT | |
| SCHEMBL1308266 | 0.79 | ABCB1 (0.52) | ABCB1ABCC1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | claimed |
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2009-11-05 | — | — | US | claimed |
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | disclosed |
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | disclosed |
| US-8053439-B2 | Benzophenone derivatives useful for inhibiting formation of microtubule | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-11-08 | — | — | US | disclosed |
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275575-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | TUBB1, TUBA1C, TUBB6 | LMNA 1935/4885SMN1; SMN2 1781/4885ABCB1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.