Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862025 | 0.79 | TSHR (0.55) | TSHRIKBKBPOLBALDH1A1L3MBTL1 | |
| SCHEMBL15998476 | 0.78 | ALDH1A1 (0.46) | NNMTTYK2POLBALDH1A1PDE4B | |
| SCHEMBL7353383 | 0.73 | LMNA (0.49) | ALDH1A1L3MBTL1 | |
| SCHEMBL27472808 | 0.70 | TSHR (0.52) | TSHR | |
| SCHEMBL18359282 | 0.69 | IKBKB (0.38) | TSHRIKBKBNR3C2POLBALDH1A1 | |
| SCHEMBL3173105 | 0.69 | TSHR (0.44) | TSHR | |
| SCHEMBL14445226 | 0.69 | MEN1 (0.34) | TSHRPDE4BKDM4E | |
| SCHEMBL2078386 | 0.69 | TSHR (0.51) | TSHR | |
| SCHEMBL26418189 | 0.68 | LMNA (0.52) | TSHRCYP2C19ALDH1A1L3MBTL1PDE4B | |
| SCHEMBL1717058 | 0.68 | TSHR (0.58) | TSHRCYP2C19ALDH1A1PDE4BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |